Alexander Zlotnik Selected Research

Traumatic Brain Injuries (Traumatic Brain Injury)

5/2022	Glutamate Efflux across the Blood-Brain Barrier: New Perspectives on the Relationship between Depression and the Glutamatergic System.
1/2022	Blood Glutamate Scavenging With Pyruvate as a Novel Preventative and Therapeutic Approach for Depressive-Like Behavior Following Traumatic Brain Injury in a Rat Model.
4/2019	Treatment of combined traumatic brain injury and hemorrhagic shock with fractionated blood products versus fresh whole blood in a rat model.
1/2016	Neuroprotection by Estrogen and Progesterone in Traumatic Brain Injury and Spinal Cord Injury.
8/2014	Brain to blood glutamate scavenging as a novel therapeutic modality: a review.
12/2012	Severe traumatic brain injury and controlled hemorrhage in rats: quest for the optimal mean arterial blood pressure after whole fresh donor blood resuscitation.
10/2012	Pharmacokinetics of glutamate-oxaloacetate transaminase and glutamate-pyruvate transaminase and their blood glutamate-lowering activity in naïve rats.
7/2012	The effect of blood glutamate scavengers oxaloacetate and pyruvate on neurological outcome in a rat model of subarachnoid hemorrhage.
1/2012	Cell-free DNA as a marker for prediction of brain damage in traumatic brain injury in rats.
1/2012	Effect of glutamate and blood glutamate scavengers oxaloacetate and pyruvate on neurological outcome and pathohistology of the hippocampus after traumatic brain injury in rats.

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Alexander Zlotnik Research Topics

Disease

17	Stroke (Strokes) 05/2022 - 01/2007
16	Traumatic Brain Injuries (Traumatic Brain Injury) 05/2022 - 01/2007
7	Critical Illness (Critically Ill) 10/2021 - 06/2014
6	Brain Injuries (Brain Injury) 01/2016 - 09/2012
5	Ischemic Stroke 07/2021 - 11/2011
5	Pain (Aches) 01/2021 - 10/2010
4	Postoperative Pain 01/2021 - 07/2012
4	Brain Edema (Cerebral Edema) 01/2019 - 11/2011
4	Closed Head Injuries 08/2010 - 01/2007
3	Infarction (Infarctions) 01/2019 - 11/2011
3	Fever (Fevers) 11/2015 - 10/2010
2	Hemorrhage 12/2022 - 12/2012
2	Ventilator-Associated Pneumonia 01/2021 - 03/2017
2	Hypoxia (Hypoxemia) 01/2021 - 01/2014
2	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 01/2019 - 11/2011
2	Infections 03/2017 - 09/2012
2	Hypohidrosis 11/2015 - 10/2010
2	Self Mutilation 11/2015 - 10/2010
2	Hereditary Sensory and Autonomic Neuropathies (HSAN) 11/2015 - 10/2010
2	Intellectual Disability (Idiocy) 11/2015 - 10/2010
2	Hypothermia 08/2014 - 04/2013
2	Subarachnoid Hemorrhage (Aneurysmal Subarachnoid Hemorrhage) 08/2014 - 07/2012
2	Craniocerebral Trauma (Head Injury) 03/2014 - 11/2011
2	Brain Diseases (Brain Disorder) 07/2013 - 10/2012
2	Brain Ischemia (Cerebral Ischemia) 11/2011 - 11/2010
1	Maternal Death 12/2022
1	Postpartum Hemorrhage 12/2022
1	Severe Acute Respiratory Syndrome 07/2021
1	Hypokalemia 05/2021
1	Mental Disorders (Mental Disorder) 01/2021
1	Wounds and Injuries (Trauma) 01/2021
1	Chronic Pain 01/2021
1	Guillain-Barre Syndrome 04/2020
1	Hypoalbuminemia 04/2020
1	Liver Diseases (Liver Disease) 01/2020
1	Liver Failure 01/2020
1	Hepatic Encephalopathy 01/2020
1	Shock 04/2019
1	Brain Infarction 01/2019
1	Intracranial Hemorrhages (Intracranial Hemorrhage) 01/2019

Drug/Important Bio-Agent (IBA)

23	Glutamic Acid (Glutamate)FDA Link 05/2022 - 01/2007
7	Pyruvic Acid (Pyruvate)IBA 01/2022 - 06/2008
6	Oxaloacetic Acid (Oxalacetic Acid)IBA 10/2012 - 01/2007
4	Biomarkers (Surrogate Marker)IBA 04/2020 - 07/2011
4	Neuroprotective AgentsIBA 01/2016 - 07/2009
4	Cell-Free Nucleic AcidsIBA 10/2014 - 07/2011
3	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2021 - 01/2014
3	salicylhydroxamic acid (SHAM)IBA 01/2019 - 01/2012
3	Insulin (Novolin)FDA Link 08/2014 - 10/2011
2	Anesthetics (Anesthetic Agents)IBA 07/2021 - 11/2015
2	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 01/2021 - 01/2019
2	Opioid Analgesics (Opioids)IBA 01/2021 - 01/2019
2	Analgesics (Analgesic Drugs)IBA 01/2019 - 07/2012
2	Anti-Bacterial Agents (Antibiotics)IBA 03/2017 - 01/2012
2	Progesterone FDA LinkGeneric 01/2016 - 08/2014
2	Estrogens (Estrogen)FDA Link 01/2016 - 08/2014
2	3-(2-carboxyindol-3-yl)propionic acidIBA 11/2015 - 10/2010
2	Adrenergic Agents (Adrenergic Drugs)IBA 08/2014 - 01/2012
2	Glucagon (Glukagon)FDA Link 08/2014 - 10/2011
2	Transaminases (Aminotransferases)IBA 10/2012 - 11/2011
2	Isoflurane FDA LinkGeneric 01/2012 - 08/2010
1	Tranexamic Acid (AMCA)FDA Link 12/2022
1	Pharmaceutical PreparationsIBA 05/2022
1	SteroidsIBA 10/2021
1	PotassiumIBA 05/2021
1	6-pyruvoyltetrahydropterin synthase (PTPS)IBA 01/2021
1	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 10/2020
1	mofezolacIBA 10/2020
1	Cyclooxygenase 1IBA 10/2020
1	Intravenous Immunoglobulins (IVIG)FDA Link 04/2020
1	AlbuminsIBA 04/2020
1	Proteins (Proteins, Gene)FDA Link 01/2020
1	Morphine (MS Contin)FDA LinkGeneric 01/2019
1	Bupivacaine (Bupivacaine Hydrochloride)FDA LinkGeneric 01/2019
1	Evans Blue (Blue, Evans)FDA Link 01/2019
1	Opiate AlkaloidsIBA 01/2019
1	Tramadol (K315)FDA LinkGeneric 01/2019
1	triphenyltetrazoliumIBA 01/2019
1	Dexamethasone (Maxidex)FDA LinkGeneric 01/2019
1	Acetaminophen (Paracetamol)FDA LinkGeneric 01/2019
1	Protective AgentsIBA 01/2019

Therapy/Procedure

8	Therapeutics 07/2021 - 11/2010
3	Anesthesia 07/2021 - 10/2010
3	General Anesthesia 07/2021 - 07/2012
3	Renal Dialysis (Hemodialysis) 01/2018 - 12/2012
3	Peritoneal Dialysis 01/2018 - 07/2013
2	Cesarean Section (Caesarean Section) 12/2022 - 07/2012
2	Resuscitation 04/2019 - 12/2012
2	Catheters 09/2012 - 01/2012
2	Analgesia 07/2012 - 07/2012
1	Conscious Sedation 07/2021
1	Thrombectomy 07/2021
1	Obstetrical Anesthesia 07/2021
1	Tracheostomy 01/2021
1	Thoracotomy 01/2021
1	Pain Management 01/2021
1	Length of Stay 01/2021
1	Artificial Respiration (Mechanical Ventilation) 01/2021
1	Operative Surgical Procedures 01/2019
1	Lasers (Laser) 01/2019